Carboxylic acids and derivatives
Selleck Chemical LLC GlyH-101
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4 3 M
Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 g/mol | C10H11N5NaO5PS | 100 MG
Rp-cAMPS sodium salt is a cyclic AMP analogue that acts as a competitive antagonist of cAMP-dependent protein kinase A (PKA) isoforms I and II. It is resistant to phosphodiesterase hydrolysis and supplied for research use in both solid and solution formats, suitable for biochemical and cell-based assays.
- Potent competitive antagonist of PKA I and II.
- Resistant to phosphodiesterase hydrolysis.
- High purity (≈99.7%) for reliable results.
- Soluble in water and DMSO with sonication and warming as needed.
- Available in multiple solid pack sizes and prepared solutions.
- Stable as a solid at -20°C; solutions stored frozen for limited time.
Apexbio Technology LLC 8-CPT-2Me-cAMP, sodium salt 634207-53-7 5mg
8-CPT-2Me-cAMP sodium salt (CAS 634207-53-7) is a selective agonist of exchange proteins directly activated by cAMP (EPACs) which are key intracellular cAMP sensors acting as guanine nucleotide exchange factors for Rap1 and Rap2 This compound effectively activates EPAC1 leading to increased Rap1 activity and enhanced cell adhesion particularly in the presence of MAP1A light chain 2 In Jurkat T cells 8-CPT-2Me-cAMP induces Rap1 activation independently of PKA inhibition In prostate cancer cell models it dose-dependently upregulates Epac1 phosphorylated Akt and stimulates mTORC1/mTORC2 signaling It is widely utilized to dissect EPAC-specific pathways in cell signaling adhesion and proliferation studies
Apexbio Technology LLC NADH (sodium salt)(Synonyms: Reduced β-Nicotinamide adenine dinucleotide disodium salt, NADH disodium salt), 1g, CAS: 606-68-8.
NADH (sodium salt) (CAS 606-68-8) is the reduced form of nicotinamide adenine dinucleotide functioning as an essential coenzyme involved in cellular bioenergetics Biologically NADH participates as an electron carrier in metabolic pathways including glycolysis -oxidation and the tricarboxylic acid (TCA) cycle facilitating ATP generation through electron transport In biomedical research NADH (sodium salt) is frequently applied to investigate cellular energy metabolism and elucidate mechanisms underpinning metabolic disorders
TARGETMOL CHEMICALS INC BUCINDOLOL FORMATE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Bucindolol Formatel is a blocker of (beta)1-adrenergic receptor. Bucindolol exhibits intrinsic sympathomimetic activity. Bucindolol can be used in the research of heart failure.
Apexbio Technology LLC (R)-(+)-Etomoxir sodium salt 828934-41-4 10mM (in 1mL DMSO)
(R)-( )-Etomoxir sodium salt (CAS 828934-41-4) functions as an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT-1) a mitochondrial enzyme essential for fatty acid oxidation In vitro studies show increased apoptosis in antigen-stimulated T cells cultured under low-glucose conditions upon etomoxir treatment whereas no effect is observed in high glucose environments In vivo experiments using C57BL/6 mice demonstrate reduced infiltration of immune cells including macrophages activated microglia and T cells into the central nervous system following etomoxir treatment (15 mg/kg i p ) which correlates with diminished inflammatory and demyelinating reactions Thus etomoxir serves as a valuable tool in metabolic and immunological research contexts
AdipoGen R-3-Hydroxyisobutyric acid Na
Chemical. CAS 1228078-57-6. Formula C4H7O3 . Na. MW 103.1 . 23.0. Synthetic. Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to inhibit key enzymes of the energy metabolism.
Selleck Chemical LLC Phosphoramidon Disodium Salt
Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor widely used as a biochemical tool Phosphoramidon inhibited ECE NEP and ACE activities with IC50 values of 3 5 M 0 034 M and 78 M respectively
Medchemexpress LLC Lactic acid calcium | 814-80-2 | 98.5% | 100 MG
Lactic acid calcium | 814-80-2 | 98.5% | 100 MG
Matrix Scientific TRIFLUOROACETIC ACID POTAS-25G
Trifluoroacetic acid potassium salt, 98%; 25g,C2F3KO2, MFCD00013215, mw 152.12, [2923-16-2]
TARGETMOL CHEMICALS INC CARBENOXOLONE DISODIUM 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers especially in the stomach. Antidiuretic side effects are frequent but otherwise the drug is low in toxicity. purity: 98%
Strem, An Ascensus Company CAS# 2966-50-9. 25g. Silver trifluoroacetate, min. 98%. MFCD00013199
CAS# 2966-50-9. 25g. Silver trifluoroacetate, min. 98%. MFCD00013199. Molecular Weight: 220.88. Molecular Formula: AgOOCCF3. Color/form: white to off-white pwdr. Strem# 93-4736. http://www.strem.com/catalog/v/93-4736/
eMolecules 5855-79-8 | 3-Amino-5-sulfobenzoic acid | Combi-Blocks | MFCD01825295 | 217.200 | C7H7NO5S | 95.000 | Nc1cc(cc(c1)S(O)(=O)=O)C(O)=O | 1g | 482930410
3-Amino-5-sulfobenzoic acid | Combi-Blocks | 5855-79-8 | MFCD01825295 | 217.200 | C7H7NO5S | 95.000 | Nc1cc(cc(c1)S(O)(=O)=O)C(O)=O | 1g | 482930410
Sigma Aldrich Fine Chemicals Biosciences dUTP PCR Grade sodium salt
dUTP PCR Grade is a 100 mM clear colorless SOLUTIONon of the sodium salt (pH 8.3).
TARGETMOL CHEMICALS INC BAY-299 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BAY-299 is an effecitve inhibitor of the bromodomain and PHD finger family member BRPF2 and the TATA box binding protein-associated factors TAF1 and TAF1L with IC50s of 67 nM 8 nM and 106 nM respectively. purity: 97%